Hi @harryhe,
for me this sounds alike the problem I had a few days ago. Perhaps you will take look at
/dev/mapper/vg_ucs-root does not exist - Server boots into BusyBox
I also thought that my HD would be defective, but in the end it turned out that the kernel 5.10 installed with UCS 5.0-8 caused the problem. If your system starts with the previous kernel and runs smoothly, there is a good chance that it is not a hardware defect and the solution helps from the link above.
HTH & Good Luck
Dirk